1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
|
https://en.wikipedia.org/wiki/Insulin_(medication)
https://en.wikipedia.org/wiki/Insulin_glargine
https://www.sciencehistory.org/historical-profile/frederick-banting-charles-best-james-collip-and-john-macleod
A history of insulin, and the ?two? researchers who discovered that
pig insulin was able to be substituted in dogs and in people
http://www.madehow.com/Volume-7/Insulin.html
- (bad source) how insulin is made
https://gh.bmj.com/content/3/5/e000850
https://pubmed.ncbi.nlm.nih.gov/30271626/
- Read the article through the GT paywall (PubMed)
- About how much insulin costs to manufacture
phttps://www.citizen.org/article/outrage-of-the-month-pharmas-price-gouging-on-insulin-is-literally-killing-patients/
- Has some valuable links, about how much Insulin is costing
https://www.youtube.com/watch?v=SYmvBoXi0Q8
- Channel 4 AOC talking about Campaign Finance
http://web.a.ebscohost.com.prx.library.gatech.edu/ehost/pdfviewer/pdfviewer?vid=1&sid=88e625e8-0732-4c85-aa12-a8b8cd5ded42%40sessionmgr4008
- Behind the paywall, I think
- Insulin.
- Some upcoming results about the a
https://www.opensecrets.org/political-action-committees-pacs/C00144345/summary/2020
- More money in finance stuff
- Sanofi PAC gave nearly a million, with $5K donations from employes
https://www.opensecrets.org/orgs/aetna-inc/totals?id=D000000296#totals-affiliates
- Aetna money in finance
https://www.usatoday.com/story/news/politics/2019/08/26/pharma-industry-ups-donations-senate-republicans-mcconnell/2116231001/
https://www.statnews.com/feature/prescription-politics/prescription-politics/
- General pharma industry payoffs from USA Today (meh)
https://search.proquest.com/docview/1829913470?rfr_id=info%3Axri%2Fsid%3Aprimo
- Behind the paywall
- FDA about DMCA exemption for medical devices
https://doggett.house.gov/media-center/press-releases/doggett-brown-announce-bicameral-medicare-drug-price-negotiation-bill
- Lloyd Doggett's website
- From the Public Citizen website about Medicare Negotiations
https://go.gale.com/ps/retrieve.do?tabID=T003&resultListType=RESULT_LIST&searchResultsType=SingleTab&hitCount=11184&searchType=BasicSearchForm¤tPosition=12&docId=GALE%7CA640027797&docType=Article&sort=Relevance&contentSegment=ZGPP-MOD1&prodId=ITOF&pageNum=1&contentSet=GALE%7CA640027797&searchId=R2&userGroupName=gainstoftech&inPS=true
- I don't understand it, but Patent board rules in Sanofi's favor
over a patent on PCSK9 antibodies (?)
https://gatech-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_1698956637&context=PC&vid=01GALI_GIT&lang=en_US&search_scope=primo_central&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,insulin&offset=0
- Generic insulin glargine??
- About its efficacy in a double-blind trial
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2717499
- Cost-related insulin underuse
https://www.openmarketsinstitute.org/learn/drug-prices-monopoly
- "Between 1995 and 2015, 60 pharmaceutical companies merged into just
10."
- Def not behind paywall but wow
- Lotsa good links
- the nber.org link is from this, I think
- Haven't finished reading
https://pubmed.ncbi.nlm.nih.gov/24866023/
- "Insulin glargine was the first once-daily, long-acting insulin analog
to be introduced into clinical practice more than 10 years ago and is
specifically designed to provide basal insulin requirements."
- Nice pubmed article (paywall)
"pancreatectomized dogs"
https://patents.google.com/patent/US8048854B2/en
- The patent itself
- Gives a date of 2027-07-05 for expiry
https://www.npr.org/templates/story/story.php?storyId=1869210
- 4:33 segment
- "Drug Companies Cope with Declines, May Merge"
- About the Sanofi-Aventus merger in 2004. The problem with the industry
is "a lack of new drugs"
https://healthcostinstitute.org/diabetes-and-insulin/spending-on-individuals-with-type-1-diabetes-and-the-role-of-rapidly-increasing-insulin-prices
- Some pricing data on per-unit, increases in 2012--2016, other stuff
https://www.sanofi.com/en/about-us/through-time/
- Sanofi's company history: Hoechst, Synthelabo, and Phone-Poulenc Rorer
- https://en.wikipedia.org/wiki/Hoechst_AG
- It was a holocaust bad
- Merger of like four companies (wtf) = $126B mkt cap (SNY)
https://www-proquest-com.prx.library.gatech.edu/docview/1664805626?accountid=11107
- Why is there no generic insulin?
- Kinda limited explanation
- Behind the paywall
https://www.proquest.com/docview/223927797/5F156A7B9D3F4195PQ/1?accountid=11107
- Corporate Payoffs and Pravix from Sanofi
- 2006
- Behind the paywall
https://www.ftc.gov/news-events/media-resources/mergers-competition/pay-delay
- FTC recent paydelay stuff
https://www.drugs.com/nda/mk_1293_160805.html
- Semi-reliable, probably (not a good enough source, maybe)
- Press release
- Lusduna Nexvue, a tentatively approved follow-on for glargine
https://www.fiercepharma.com/marketing/despite-scoring-fda-nod-merck-s-follow-med-lusduna-must-wait-to-challenge-lantus
- Doesn't exactly fit the narrative, but these are other big companies
- Plus the Hatch whatever act
- Nevermind, it does. So these massive companies just got into the
mkt to sell at the $300 prices. WTF
- Sanofi has two competitor insulin glargines
https://projects.propublica.org/represent/lobbying/search?commit=Search&fields%5B%5D=_all&page=2&search=sanofi&utf8=%E2%9C%93
- The current lobbying projects that Sanofi is doing. I didn't get much
https://www.opensecrets.org/Lobby/clientsum.php?id=D000000215&year=2020
- Another lobbying site
- Sanofi put out $4M in lobbying!
https://go.gale.com/ps/i.do?p=GPS&u=gainstoftech&id=GALE|A202627653&v=2.1&it=r
- 2009: "Sanofi-Aventis in acquisition mode"
- Uhh I don't think this will be useful, but it's here.
- What I really want to know is how many companies has Sanofi/its
predecessors acquired.
https://pharmaphorum.com/articles/a_history_of-_sanofi/
- Might be a wiki citation, so good
- Includes some merger info, might be incomplete on the Aventis side but
prob pretty comprehensive
https://www.nber.org/system/files/working_papers/w7280/w7280.pdf
- I didn't have time to read it
- 60 pages on antitrust laws (and court?)
https://go.gale.com/ps/retrieve.do?tabID=Journals&resultListType=RESULT_LIST&searchResultsType=MultiTab&hitCount=6&searchType=BasicSearchForm¤tPosition=2&docId=GALE%7CA101569966&docType=Article&sort=Relevance&contentSegment=ZICC-MOD1&prodId=CSIC&pageNum=1&contentSet=GALE%7CA101569966&searchId=R2&userGroupName=gainstoftech&inPS=true
- "Physicians and the pharmaceutical industry: a dysfunctional
relationship"
- Skimmed it. Seems useful?
|